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In terms of glycemic effects, GLP-1RAs reduce mean HbA1c by 0.55-1.2% versus placebo in patients with T2D, with exaggerated effects seen with longer-acting agents 43
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Novo Nordisk, a pharmaceutical company based in Denmark, made the first of the recent blockbuster drugs, Ozempic, which emerged on the scene as a drug for people with diabetes
The drugs have large molecules that make that very difficult, if not impossible, he notes
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